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Prefix that means "very small"

Looking for the answer to the USA Today Crossword clue “Prefix that means "very small"”? The solution is NANO, a 4-letter word. This clue was most recently seen in the July 6, 2026 (Monday) USA Today Crossword. Tap any date below to open that day's complete puzzle, or search another clue from the bar above.

Answer
NANO

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