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Psychoactive desert plant

Looking for the answer to the USA Today Crossword clue “Psychoactive desert plant”? The solution is PEYOTE, a 6-letter word. This clue was most recently seen in the August 2, 2026 (Sunday) USA Today Crossword. Tap any date below to open that day's complete puzzle, or search another clue from the bar above.

Answer
PEYOTE

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