Mississippi's region

Nora Whitfield Crossword Editor · Verified answers

Looking for the answer to the USA Today Up & Down Words clue “Mississippi's region”? The solution is DEEP SOUTH, a two-word phrase and answer #1 in the daily word chain. This clue was most recently seen in the October 22, 2026 (Thursday) puzzle. The second word of each answer starts the next — see the full chain below.

Answer

DEEPSOUTH

Last appearance

October 22, 2026ThursdayDEEP SOUTH

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